Has there been a new breakthrough in AI for developing antibiotics?

Has there been a new breakthrough in AI for developing antibiotics?

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  • User 2023-12-24 01:51:45

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T break is part of an emerging a of research aims to use AI antibiotic disc y design Gkvi. use of AI dramatic y cuts time it takes to rt thous s of promising compounds accelerating drug disc y process Utlyvbxmv.
compounds disc ed by researc s s low toxicity st human cells Mpfbnc making m good drug c idates. researc s sh d ir findings Ph Bio Wtgyskemckz a nonprofit started by Collins ot s part of Antibiotics-AI Project. nonprofit plans to do detailed analysis of chemical properties potential of se compounds Triji.
researc s tested 283 promising compounds in mice found s al were effective st methicillin-resistant Staphylococcus aureus (MRSA) vancomycin-resistant enterococci Tcupuxlhgilx among stubbornly hard-to-kill pathogens. AI model used in t research is "explainable" meaning possible to st biochemistry behind re oning Mvjin.
T development is signifi t antibiotic resistance is among biggest global threats to human health Jdjuygcqw responsible an estimated 1.27 million deaths in 2019 contri ing to ly five million Tetyyffc. problem h worsened COVID-19 p emic no new cl ses of antibiotics developed decades Mkqfrnmgw.
How Mndqvw important to e se new antibiotic c idates need to go testing refinement y be used clinic y. T includes systematic toxicity studies pre-IND (investigational new drug) studies Varehv. Despite se necessary steps disc y of a new cl s of antibiotics using AI is a signifi t advancement in fight st antibiotic resistance Ljnccyq. Afgcm.
A team of researc s at laboratory of James Collins of Broad Institute of M sachusetts Institute of Technology Harvard University h made a signifi t break in field of antibiotic disc y using artificial intelligence (AI) Pxrl. y used a type of AI k n deep learning to screen millions of compounds antibiotic activity Crmscyb.

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